Search Results - Diagnostics+%3e+Biomarkers

4 Results Sort By:
TMEPAI for Diagnosis and Treatment of Breast Cancer
UT Health San Antonio researchers have developed an assay that detects overexpression of TMEPAI, a potential biomarker for aggressive cancer growth and invasion in TNBC patients. Dr. Saikumar’s team has identified compounds that inhibit the expression of TMEPAI and thus may represent therapeutic candidates to inhibit cancer proliferation and...
Published: 3/26/2021   |   Inventor(s): Pothana Saikumar, Prajjal Singha
Keywords(s):  
Category(s): Clinical Specialty > Oncology, Clinical Specialty > Women's Health, Diagnostics > Biomarkers, Therapeutics > Small Molecule
Inducing Chemotherapeutic Sensitivity in Hyper-Transcription Diseases
This discovery is a method for the induction of sensitivity in tumor cells to a synergistic combination of PARP1 and ATR inhibition. It is applicable to hyper-transcription diseases , primarily cancers, including: Ewing sarcoma, acute myeloid leukemia, breast cancer, myelodysplastic syndrome, and possibly even Alzheimers and ALS. Background:Modern treatment...
Published: 8/23/2018   |   Inventor(s): Alexander Bishop, Aparna Gorthi, Carolina Romero, Liesl Lawrence, CPRIT
Keywords(s):  
Category(s): Clinical Specialty > Hematology, Clinical Specialty > Oncology, Clinical Specialty > Orthopedics, Diagnostics > Biomarkers, Diagnostics > Assay
Non-Invasive Screening for Endometriosis
This invention is a diagnostic for endometriosis based on a screening method which uses menstrual samples to perform single-cell analysis of gene expression by PCR. This diagnostic test uses a unique panel of genes whose expression patterns can be used to distinguish between not only endometriosis positive and endometriosis negative samples, but also...
Published: 5/17/2018   |   Inventor(s): Nameer Kirma, Bruce Nicholson
Keywords(s):  
Category(s): Clinical Specialty > Women's Health, Diagnostics > Biomarkers
ANGPTL4 as prognostic marker for bladder cancer
Researchers at UT Health SA have discovered a less invasive method to monitor for recurrence of bladder cancer. Using Angiopoietin-like 4 protein (ANGPTL4) as a prognostic indicator, clinicians would be able to use a urine sample to monitor the likelihood of recurrence of non-muscle invasive bladder cancer. Background:Non-muscle invasive bladder cancers...
Published: 3/6/2018   |   Inventor(s): Rita Ghosh, Roble Bedolla, Eduardo Cardenas, Neelam Mukherjee, Tiffani Houston
Keywords(s):  
Category(s): Diagnostics > Biomarkers, Clinical Specialty > Oncology, Clinical Specialty > Urology