Biosensors for Air or Fluid Leaks After Surgery

Tech ID:
2011.079.HSCS
Description:

This device is a multifaceted platform technology that can perform a variety of functions including, but not limited to, measuring cardiac output after heart surgery, detecting air leaks after lung surgery. The device can directly measure physiological changes at a desired organ, tissue, and/or site. This site may be any portion of the body including heart, lungs, gastrointestinal tract, or proximate other organs.

 

Background:

Decrease in cardiac contractility may occur due to myocardial ischemia, rejection or reperfusion injury in cardiac transplantation, fluid overload in the case of congestive heart failure, or other injury or pathology of the myocardium. Currently there is no direct method available to measure the cardiac contractility. Direct measurement of cardiac contractility is important as it could represent a means of earlier identification of cardiac failure allowing for earlier intervention. This new device contains sensors that can detect movement of organs or leaks proximate to the site where the sensors are disposed and could be used to directly measure cardiac contractility.

 

This device can also measure lung compliance with high sensitivity without damaging the lung tissue. Lung compliance, like cardiac contractility, may change in certain pathological conditions such as pulmonary edema, pulmonary injury, pulmonary infection, respiratory distress syndrome, or graft rejection or ischemia/reperfusion injury after lung transplant. The device could be used to measure pathologic changes in other tissues as a result of edema, ischemia, infection, rejection, or other pathology.

 

This device consists of electrolytic biosensors embedded in a flexible, porous protective matrix. The porous matrix may be positioned in a body at a site to be monitored and the flexible material allows a shape to be selected to facilitate impedance monitoring at a desired site. The sensors can be configured to analyze, calculate and/or display impedance at the desired site or organ. The sensors can externally transmit impedance data and related messages using existing network infrastructure and/or to mobile user device.

 

Commercial Applications & Advantages:

The invention has applicability to several different medical disciplines and provides the following benefits:

·         Accurate and direct measurement of the physiological state of an organ

·         Allows the medical team to diagnose problems early, before the development severe complications

·         Electrolytic biosensor can transmit patient data and related messages using existing network infrastructure and/or to mobile user device

·         Simple and robust components offers built-in reliability and low per-unit costs

·         Adoption of the device does not require any change in the practice of clinicians

·         Small size and portability facilitates bedside use

Patent Information:
For information contact:
John Fritz
Sr. Business Development Manager
fritzja@utshcsa.edu
210-562-4033
Inventors:
Daniel Dearmond
Keywords: