PET Tracers for alpha-synuclein ( a-syn) Imaging

Tech ID:
HSC-1616

There are no known specific ligands for alpha-synuclein PET imaging. Molecular docking studies were carried out with beta-Amyloid and tau proteins. We found ten molecules that sowed higher affinity towards alpha-synuclein over beta-Amyloid and tau.

 

Our goal is to find a alpha-synuclein lead PET ligand by in vitro and in vivo studies. These will be placed in clinical studies for Parkinson's disease early stage diagnosis by PET imaging.

For information contact:
Daniel Rafferty
Business Development Manager
raffertyde@uthscsa.edu
(210) 562-4038
Inventors:
Ramesh Neelamegam
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