Osteocyte Cell Lines

Tech ID:
1997.008.HSCS
Description:
Researchers at UT Health San Antonio have developed a method of producing osteocyte cell line in various stages of differentiation. Such cell line remains stable after more than 20 passages. The osteocyte has a stellate shape with dendritic processes and expresses high level of osteocalcin. More specifically, it provides a method of production for cultured osteocytes of various differentiation stages. Furthermore, it relates to osteocyte cell line, and more specifically cultured osteocyte. The invention also relates to a method for the production of monoclonal antibodies using such cultured osteocytes and further relates to hybridomas and monoclonal antibodies which recognize an osteocyte-specific antigen. Finally, the invention relates to a method of screening for modification factors and binding factors for osteocytes.

IP Status:            US 6,358,737, Issued March 19, 2002

Patent Information:
Category(s):
Biologics
For information contact:
Daniel Rafferty
Business Development Manager
Office of Technology Commercialization
raffertyde@uthscsa.edu
Inventors:
Lynda Bonewald
Yoichi Kato
Keywords:
Biologics