Search Results - Therapeutics > Biologics

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Novel Micro RNA as a Tumor Suppressor
The miRNA miR-185 has been shown to inhibit cell proliferation, anchorage independent growth, cell invasion as well as tumor growth and metastasis in immuno-compromised mice. In addition to it success being systemically delivered to treat tumor growth and metastasis in mice, miR-185 sensitizes resistant cancer cells to cancer treatment drugs inclu...
Published: 4/23/2015   |   Inventor(s): Manjeet Rao, J. Saadi Imam
Keywords(s):  
Category(s): Therapeutics > Biologics, Clinical Specialty > Oncology
Non-Hydrolysable ATP for Treatment of Cancer
UT Health San Antonio scientists have discovered that non-hydrolysable forms of ATP reduce cell migration and proliferation in metastatic cancers.Background:ATP (adenosine 5'-triphosphate) has been proposed as a therapeutic agent to improve nutritional status, reduce fatigue, reduce side effects associated with chemotherapy, and promote overall qua...
Published: 4/16/2015   |   Inventor(s): Jean Jiang, Jade Zifei Zhou
Keywords(s):  
Category(s): Therapeutics > Biologics, Clinical Specialty > Oncology
miRNAs for Treatment of Drug Resistant Breast Cancers
Researchers at UT Health San Antonio have identified a microRNA that can uniquely sensitize drug-resistant, triple-negative breast cancer to chemotherapy drugs such as paclitaxel, providing a novel and potent potential therapeutic approach with lower toxicity and reduced side effects.BackgroundDisease-free survival is short-lived for women with tri...
Published: 4/10/2015   |   Inventor(s): Manjeet Rao, J. Saadi Imam, Behyar Zoghi, YaO-FU-Chang, Panneerdoss Subbarayalu
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Category(s): Life Sciences Research Tools > Biomarkers, Therapeutics > Biologics, Clinical Specialty > Oncology, Clinical Specialty > Women's Health
Specific Inhibitors of Reactive Oxygen Species (ROS) Production
UT Health San Antonio researchers have created recombinant mutant versions of NOXA1 and p67phox that inhibit generation of reactive oxygen species (ROS) by NOX enzymes. These polypeptides may be useful therapeutically as specific inhibitors of ROS overproduction to treat a variety of disease states.Background:ROS are important for a number of norm...
Published: 4/11/2013   |   Inventor(s): Anthony Valente, Robert Clark
Keywords(s): Biologics, Drugs
Category(s): Therapeutics > Biologics