Search Results - Therapeutics > Biologics

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Non-Hydrolysable ATP for Treatment of Cancer
UT Health San Antonio scientists have discovered that non-hydrolysable forms of ATP reduce cell migration and proliferation in metastatic cancers.Background:ATP (adenosine 5'-triphosphate) has been proposed as a therapeutic agent to improve nutritional status, reduce fatigue, reduce side effects associated with chemotherapy, and promote overall qua...
Published: 4/16/2015   |   Inventor(s): Jean Jiang, Jade Zifei Zhou
Keywords(s):  
Category(s): Therapeutics > Biologics, Clinical Specialty > Oncology
miRNAs for Treatment of Drug Resistant Breast Cancers
Researchers at UT Health San Antonio have identified a microRNA that can uniquely sensitize drug-resistant, triple-negative breast cancer to chemotherapy drugs such as paclitaxel, providing a novel and potent potential therapeutic approach with lower toxicity and reduced side effects.Background:Disease-free survival is short-lived for women with tr...
Published: 4/10/2015   |   Inventor(s): Manjeet Rao, J. Saadi Imam, Behyar Zoghi, Yao-Fu-Chang, Panneerdoss Subbarayalu
Keywords(s):  
Category(s): Life Sciences Research Tools > Biomarkers, Therapeutics > Biologics, Clinical Specialty > Oncology, Clinical Specialty > Women's Health
Specific Inhibitors of Reactive Oxygen Species (ROS) Production
UT Health San Antonio researchers have created recombinant mutant versions of NOXA1 and p67phox that inhibit generation of reactive oxygen species (ROS) by NOX enzymes. These polypeptides may be useful therapeutically as specific inhibitors of ROS overproduction to treat a variety of disease states.Background:ROS are important for a number of norm...
Published: 4/11/2013   |   Inventor(s): Anthony Valente, Robert Clark
Keywords(s): Biologics, Drugs
Category(s): Therapeutics > Biologics