Search Results - Therapeutics > Biologics

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Method of targeting liposomes to bone marrow
UT Health San Antonio and Waseda University in Shinjuku, Japan have collaboratively developed a drug delivery system capable of delivering a cargo preferentially to bone marrow. This drug delivery system shows promise for therapeutic and diagnostic applications for which the cells of the bone marrow play an important role. Background:Targeted ant...
Published: 10/16/2018   |   Inventor(s): William Phillips, Beth Goins, Keitaro Sou, Shinji Takeoka, Eishun Tsuchida
Keywords(s): Biologics, Drugs
Category(s): Clinical Specialty > Oncology, Therapeutics > Biologics, Therapeutics > Other
Micro-RNA Therapy for High-Risk Pediatric Brain Cancer
A MicroRNA therapy has been developed for the purpose of increasing the chemo- and radio-sensitivity of tumor cells in Medulloblastoma. The invention would allow for lower dosages of radiation and chemotherapy by working synergistically with these therapies, thus reducing adverse side effects. It may also lead to more complete eradication of the tu...
Published: 9/25/2018   |   Inventor(s): Manjeet Rao, Nourhan Abdelfattah
Keywords(s):  
Category(s): Therapeutics > Biologics, Therapeutics > Nucleic Acids, Clinical Specialty > Neurology, Clinical Specialty > Oncology, Clinical Specialty > Pediatrics
Non-Hydrolysable ATP for Treatment of Cancer
UT Health San Antonio scientists have discovered that non-hydrolysable forms of ATP reduce cell migration and proliferation in metastatic cancers.Background:ATP (adenosine 5'-triphosphate) has been proposed as a therapeutic agent to improve nutritional status, reduce fatigue, reduce side effects associated with chemotherapy, and promote overall qua...
Published: 4/16/2015   |   Inventor(s): Jean Jiang, Jade Zifei Zhou
Keywords(s):  
Category(s): Therapeutics > Biologics, Clinical Specialty > Oncology
miRNAs for Treatment of Drug Resistant Breast Cancers
Researchers at UT Health San Antonio have identified a microRNA that can uniquely sensitize drug-resistant, triple-negative breast cancer to chemotherapy drugs such as paclitaxel, providing a novel and potent potential therapeutic approach with lower toxicity and reduced side effects.Background:Disease-free survival is short-lived for women with tr...
Published: 4/10/2015   |   Inventor(s): Manjeet Rao, J. Saadi Imam, Behyar Zoghi, Yao-Fu-Chang, Panneerdoss Subbarayalu
Keywords(s):  
Category(s): Life Sciences Research Tools > Biomarkers, Therapeutics > Biologics, Clinical Specialty > Oncology, Clinical Specialty > Women's Health
Specific Inhibitors of Reactive Oxygen Species (ROS) Production
UT Health San Antonio researchers have created recombinant mutant versions of NOXA1 and p67phox that inhibit generation of reactive oxygen species (ROS) by NOX enzymes. These polypeptides may be useful therapeutically as specific inhibitors of ROS overproduction to treat a variety of disease states.Background:ROS are important for a number of norm...
Published: 4/11/2013   |   Inventor(s): Anthony Valente, Robert Clark
Keywords(s): Biologics, Drugs
Category(s): Therapeutics > Biologics