Search Results - drugs

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Cytotoxic compounds from invasive salvinias (Salvinia spp.) against human tumor cells
Novel plant-derived compounds that have cytotoxic properties against cancer cells and therefore may be potent anticancer therapeutics. These compounds are derived from giant salvinia, one of the most noxious invasive species of plants in the world. The compounds showed selective cytotoxic activity against several human cancer cell lines, including ...
Published: 4/23/2013   |   Inventor(s): Shiyou Li, Ping Wang, Guangrui Deng, Wei Yuan, Zushang Su
Keywords(s): Drugs
Category(s): Therapeutics
Specific Inhibitors of Reactive Oxygen Species (ROS) Production
Texas Health San Antonio researchers have created recombinant mutant versions of NOXA1 and p67phox that inhibit generation of reactive oxygen species (ROS) by NOX enzymes. These polypeptides may be useful therapeutically as specific inhibitors of ROS overproduction to treat a variety of disease states. Background: ROS are important for a number o...
Published: 4/11/2013   |   Inventor(s): Anthony Valente, Robert Clark
Keywords(s): Biologics, Drugs
Category(s): Therapeutics
A method to better predict the likelihood that endocrine therapy alone after surgical intervention will be sufficient to treat patients with estrogen-receptor-positive breast cancer
The University of Texas Health Science Center at San Antonio seeks to partner with a diagnostic products company to develop and commercialize a clinical diagnostic with the potential to determine if a patient with estrogen receptor (ER) positive breast cancer is suitable for treatment with endocrine therapy (e.g., tamoxifen and/or the aromatase inh...
Published: 2/7/2013   |   Inventor(s): Amy Trauernicht, Thomas Boyer
Keywords(s): Biologics, Drugs
Category(s): Diagnostics
Novel Method for Greatly Increasing Liposomal Drug Delivery to Lymph Nodes
This invention provides a method of targeting colloids to the lymph nodes and retaining the colloids in the lymph nodes for an extended period of time. The colloids can be used for imaging and/or for delivery of therapeutic agents. The sentinel lymph node is the first lymph node encountered by metastatic tumor cells that have escaped from the pri...
Published: 5/30/2012   |   Inventor(s): Beth Goins, William Phillips
Keywords(s): Drugs
Category(s): Medical Devices > Imaging