Search Results - drugs

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Method of targeting liposomes to bone marrow
UT Health San Antonio and Waseda University in Shinjuku, Japan have collaboratively developed a drug delivery system capable of delivering a cargo preferentially to bone marrow. This drug delivery system shows promise for therapeutic and diagnostic applications for which the cells of the bone marrow play an important role. Background:Targeted ant...
Published: 10/16/2018   |   Inventor(s): William Phillips, Beth Goins, Keitaro Sou, Shinji Takeoka, Eishun Tsuchida
Keywords(s): Biologics, Drugs
Category(s): Clinical Specialty > Oncology, Therapeutics > Biologics, Therapeutics > Other
Salvinia Cyctotoxic Compounds for Treatment of Cancer
Novel plant-derived compounds that have cytotoxic properties against cancer cells and therefore may be potent anticancer therapeutics have been discovered by UT Health San Antonio researchers. These compounds are derived from giant salvinia, one of the most noxious invasive species of plants in the world. The compounds showed selective cytotoxic ac...
Published: 4/23/2013   |   Inventor(s): Shiyou Li, Ping Wang, Guangrui Deng, Wei Yuan, Zushang Su
Keywords(s): Drugs
Category(s): Therapeutics > Small Molecule, Clinical Specialty > Oncology
Specific Inhibitors of Reactive Oxygen Species (ROS) Production
UT Health San Antonio researchers have created recombinant mutant versions of NOXA1 and p67phox that inhibit generation of reactive oxygen species (ROS) by NOX enzymes. These polypeptides may be useful therapeutically as specific inhibitors of ROS overproduction to treat a variety of disease states.Background:ROS are important for a number of norm...
Published: 4/11/2013   |   Inventor(s): Anthony Valente, Robert Clark
Keywords(s): Biologics, Drugs
Category(s): Therapeutics > Biologics
Endocrine Therapy Diagnostic for ER+ Breast Cancer
UT Health San Antonio seeks to partner with a diagnostic products company to develop and commercialize a clinical diagnostic with the potential to determine if a patient with estrogen receptor (ER) positive breast cancer is suitable for treatment with endocrine therapy (e.g., tamoxifen and/or the aromatase inhibitors anastrozole (Arimidex®), le...
Published: 2/7/2013   |   Inventor(s): Amy Trauernicht, Thomas Boyer
Keywords(s): Biologics, Drugs
Category(s): Diagnostics > Assay, Clinical Specialty > Oncology, Clinical Specialty > Women's Health
Colloid Radiolabel or Drug Delivery to Lymph Nodes
This invention provides a method of targeting colloids to the lymph nodes and retaining the colloids in the lymph nodes for an extended period of time. The colloids can be used for imaging and/or for delivery of therapeutic agents. The sentinel lymph node is the first lymph node encountered by metastatic tumor cells that have escaped from the pri...
Published: 5/30/2012   |   Inventor(s): Beth Goins, William Phillips
Keywords(s): Drugs
Category(s): Medical Devices > Imaging