Search Results - cara gonzales

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Novel Polygodial Analogs to Treat Cancer
Novel polygodial analogs for the treatment of cancer and other proliferative diseases have been developed by researchers at UT Health San Antonio. These analogs are effective in inhibiting cell proliferation both in vitro and in vivo, without the observable side effects attributed to the parent compound. Moreover, these analogs may have potential a...
Published: 10/16/2018   |   Inventor(s): Cara Gonzales, Alex Kornienko, Ramesh Dasari
Keywords(s):  
Category(s): Clinical Specialty > Dentistry, Clinical Specialty > Oncology, Therapeutics > Small Molecule
Novel Capsazepine Analogs to Treat Cancer
Novel compounds have been developed based upon the capsazepine pharmacophore that are effective in halting tumor cell proliferation in vitro and in vivo. Capsazepine is a known, off-patent, analog of Capsaicin that has been proposed and studied as a TRPV1 antagonist for treatment of pain. Although Capsazepine has been proposed for alleviation of p...
Published: 8/23/2018   |   Inventor(s): Cara Gonzales, Stanton McHardy
Keywords(s):  
Category(s): Clinical Specialty > Oncology, Therapeutics > Small Molecule
Use of Capsazepine and Analogs for Treatment of Cancer
A UT Health San Antonio scientist has discovered that local intra-tumoral injection of Capsazepine offers an effective treatment to reduce tumor cell proliferation in solid tumors. Capsazepine is a known, off-patent, analog of Capsaicin that has been proposed and studied as a TRPV1 antagonist for treatment of pain. Background:Capsazepine and anal...
Published: 4/16/2015   |   Inventor(s): Cara Gonzales
Keywords(s):  
Category(s): Therapeutics > Analgesics