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CsA treatment for BRCA1 mutant cancers
I have demonstrated that BRCA1-mutant triple-negative breast cancer (TNBC) cells are highly sensitive to cyclosporine (CsA) and non-immunosuppressive CsA-derivatives (NIM811 or Alisporivir). To determine whether CsA would also be effective in treating BRCA1-mutant TNBC cells in vivo, I set up a pilot study using a preclinical xenograft model to investigate...
Published: 10/5/2021
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Inventor(s):
Kimi Yuk-Ling Kong
Keywords(s):
Category(s):
Clinical Specialty > Oncology
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Clinical Specialty > Women's Health
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Clinical Specialty > Endocrinology
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Life Sciences Research Tools > Drug Screening
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Therapeutics > Small Molecule