Search Results - Clinical+Specialty+%3e+Women%27s+Health

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TMEPAI for Diagnosis and Treatment of Breast Cancer
UT Health San Antonio researchers have developed an assay that detects overexpression of TMEPAI, a potential biomarker for aggressive cancer growth and invasion in TNBC patients. Dr. Saikumar’s team has identified compounds that inhibit the expression of TMEPAI and thus may represent therapeutic candidates to inhibit cancer proliferation and...
Published: 3/26/2021   |   Inventor(s): Pothana Saikumar, Prajjal Singha
Category(s): Clinical Specialty > Oncology, Clinical Specialty > Women's Health, Diagnostics > Biomarkers, Therapeutics > Small Molecule
CsA treatment for BRCA1 mutant cancers
I have demonstrated that BRCA1-mutant triple-negative breast cancer (TNBC) cells are highly sensitive to cyclosporine (CsA) and non-immunosuppressive CsA-derivatives (NIM811 or Alisporivir). To determine whether CsA would also be effective in treating BRCA1-mutant TNBC cells in vivo, I set up a pilot study using a preclinical xenograft model to investigate...
Published: 2/14/2020   |   Inventor(s): Kimi Yuk-Ling Kong
Category(s): Clinical Specialty > Oncology, Clinical Specialty > Women's Health, Clinical Specialty > Endocrinology, Life Sciences Research Tools > Drug Screening, Therapeutics > Small Molecule
Non-Invasive Screening for Endometriosis
This invention is a diagnostic for endometriosis based on a screening method which uses menstrual samples to perform single-cell analysis of gene expression by PCR. This diagnostic test uses a unique panel of genes whose expression patterns can be used to distinguish between not only endometriosis positive and endometriosis negative samples, but also...
Published: 5/17/2018   |   Inventor(s): Nameer Kirma, Bruce Nicholson
Category(s): Clinical Specialty > Women's Health, Diagnostics > Biomarkers
miRNAs for Treatment of Drug Resistant Breast Cancers
Researchers at UT Health San Antonio have identified a microRNA that can uniquely sensitize drug-resistant, triple-negative breast cancer to chemotherapy drugs such as paclitaxel, providing a novel and potent potential therapeutic approach with lower toxicity and reduced side effects.Background:Disease-free survival is short-lived for women with triple-negative...
Published: 4/10/2015   |   Inventor(s): Manjeet Rao, J. Saadi Imam, Behyar Zoghi, Yao-Fu Chang, Panneerdoss Subbarayalu
Category(s): Life Sciences Research Tools > Biomarkers, Therapeutics > Biologics, Clinical Specialty > Oncology, Clinical Specialty > Women's Health
Advanced Cervical Ripening System (ACRS)
UT Health San Antonio researchers have developed a unique method for advanced cervical ripening which causes the effacement and thinning that occurs in natural child birth. This advanced cervical ripening system is superior to traditional methods because the unique design allows for uniform ripening by adapting to the geometry of each patient, and...
Published: 12/17/2013   |   Inventor(s): Brent Nowak, Leonid Bunegin
Category(s): Medical Devices > Surgical Equipment, Clinical Specialty > Women's Health
Endocrine Therapy Diagnostic for ER+ Breast Cancer
UT Health San Antonio seeks to partner with a diagnostic products company to develop and commercialize a clinical diagnostic with the potential to determine if a patient with estrogen receptor (ER) positive breast cancer is suitable for treatment with endocrine therapy (e.g., tamoxifen and/or the aromatase inhibitors anastrozole (Arimidex®), letrozole...
Published: 2/7/2013   |   Inventor(s): Amy Trauernicht, Thomas Boyer
Keywords(s): Biologics, Drugs
Category(s): Diagnostics > Assay, Clinical Specialty > Oncology, Clinical Specialty > Women's Health